THE RELATIONSHIP BETWEEN SUN EXPOSURE AND MALIGNANT SUBCUTANEOUS MELANOMA: A SCIENTIFIC REVIEW

Abstract

Among skin cancers, malignant subcutaneous melanoma has seen an increase in its incidence in several parts of the world. Furthermore, it is known for its strong aggressiveness and rapid tumor development. This review sought to analyze and synthesize the existing literature on the relationship between sun exposure and malignant subcutaneous melanoma, studying the mechanism of carcinogenesis and presenting possibilities for prophylaxis. The systematic review was conducted by combining results from qualitative and quantitative studies. This approach allowed a more comprehensive and in-depth understanding of the topic in question. It was concluded that UV-B rays are mainly responsible for the damage to cellular DNA that leads to melanoma carcinogenesis and therefore highlights the importance of photoprotection and limiting chronic sun exposure, considering that the damage is generally irreversible and cumulative.